Small molecule crystallography: insight into biological activity
نویسندگان
چکیده
منابع مشابه
Crystallography of Biological Small Molecules
C278 P.05.08.4 Acta Cryst. (2005). A61, C278 Synthesis and Structural Characterization of 3-(4-fluorophenyl)2-( -naphtyl)-1,3-thiazolidin-4-one José Luis Pinto Camargo, J. A. Henao, W. Rodríguez, V. V. Kouznetsov, Grupo de Investigación en Química Estructural, Centro de Investigación en Biomoléculas “CIBIMOL”, Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, A. A. ...
متن کاملStructural Insight into a Biofilm Signaling Molecule
Life as a bacterium presents special challenges—primary among them the need to sense and respond to the environment—which for an organism just 3 micrometers long, like Pseudomonas aeruginosa, might seem a daunting prospect. One way Pseudomonas and other bacteria cope with the rigors of existence is by forming highly organized communities called biofilms. As members of a biofilm, microbes gain a...
متن کاملNon-merohedral Twinning in Small Molecule and Protein Crystallography
In contrast to twinning by merohedry the reciprocal lattices of the different domains of non-merohedral twins do not overlap exactly. If both twin domains are similar in size, there are often problems with the cell determinations and usual automatic indexing programs fail. But nowadays there are several programs that can deal with such kinds of problems [1], [2], [3]. In principle two different...
متن کاملBionics: biological insight into mechanical design.
www.pnas.org/cgi/content/full/96/25/14208#otherarticles This article has been cited by other articles: E-mail Alerts . click here at the top right corner of the article or Receive free email alerts when new articles cite this article sign up in the box Rights & Permissions www.pnas.org/misc/rightperm.shtml To reproduce this article in part (figures, tables) or in entirety, see: Reprints www.pna...
متن کاملStructural insight into inactivation of plasminogen activator inhibitor-1 by a small-molecule antagonist.
Plasminogen activator inhibitor-1 (PAI-1), a serpin, is the physiological inhibitor of tissue-type and urokinase-type plasminogen activators and thus also an inhibitor of fibrinolysis and tissue remodeling. It is a potential therapeutic target in many pathological conditions, including thrombosis and cancer. Several types of PAI-1 antagonist have been developed, but the structural basis for the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 1987
ISSN: 0108-7673
DOI: 10.1107/s0108767387085441